Chargers vs. Raiders: Week 2 Monday Night Football Prediction, Odds, and Picks
The Los Angeles Chargers and the Las Vegas Raiders, both coming off Week 1 wins, will clash in an AFC West showdown on Monday Night Football in Week 2 of the 2025 NFL season. The game takes place in Sin City at Allegiant Stadium.
Game Information and Betting Odds
The game is scheduled for a 10 p.m. ET kickoff. According to the latest odds, the Chargers are a 3.5-point favorite. The over/under for total points scored is set at 46.5. The money line has Los Angeles at -185 and Las Vegas at +154. Before placing any bets, consult the SportsLine projection model for expert analysis.
- Chargers vs. Raiders Spread: Chargers -3.5 at DraftKings Sportsbook
- Chargers vs. Raiders Over/Under: 46.5 points
- Chargers vs. Raiders Money Line: LAC -185, LV +154
- Chargers vs. Raiders Picks: See picks at SportsLine
- Chargers vs. Raiders Streaming: Fubo (Try for free)
Why the Chargers Could Cover
The Chargers have a strong recent history against the Raiders, winning four of the last five matchups and sweeping the 2024 season series while also covering the spread in both games. They went 12-5-0 against the spread in 2024 and are 6-3-1 ATS in their last 10 games against AFC West opponents, including their Week 1 upset of the Kansas City Chiefs.
Justin Herbert impressed in Week 1, throwing for 318 yards and three touchdowns. His receiving corps, featuring Ladd McConkey, Quentin Johnston, and Keenan Allen, exploited the Chiefs' defense. This could be a key factor against a Raiders defense that allowed 276 passing yards in Week 1.
Why the Raiders Could Cover
While the Raiders' record against the spread in 2024 was inconsistent, their new-look offense demonstrated potential in Week 1, registering 389 total yards against the New England Patriots. They now face a Chargers defense that allowed 347 total yards to the Chiefs. This bodes well for Geno Smith, who threw for 210 yards and two touchdowns in his last game against Los Angeles.
The Chargers limited the Chiefs to 98 rushing yards in Week 1 but will have a tougher challenge against Ashton Jeanty in Week 2.
Raiders vs. Chargers: How to Make Your Picks
The SportsLine model leans towards the under for this NFL Week 2 Monday Night Football game and indicates that one side of the spread has a greater than 50% chance of hitting. For expert analysis and picks, visit SportsLine.
Who wins Chargers vs. Raiders, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the Raiders vs. Chargers spread you need to jump on, all from the model that is 33-17 on top-rated picks since 2024, and find out.